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A Closer Look

RESEARCH GRANT AWARDS

AWARDS LIST.

Totals by Year

2023 - $891,364

2022 - $1,199,966

2021 - $749,812

2020 - $630,000

2019 - $690,000

2018 - $750,000

2017 - $747,772

2016 - $720,000

2015 - $840,000

2014 - $810,000

2013 - $808,500

2012 - $720,000

2011 - $599,780

2010 - $438,000

2009 - $435,000

2008 - $619,993

2007 - $232,600

2006 - $384,551

Amounts flagged (*) below are 50% funded by Cancer League of Colorado and 50% matched by MDC/RICHMOND AMERICAN HOMES FOUNDATION.

Swati G. Patel, MD, MS

Identification of Hereditary Cancer Syndromes through Advanced Polyps

 $     30,000

2020

Molishree Joshi, PhD

A novel CRISPR-mediated tumor targeting strategy for Liiposarcoma

 $     30,000

2020

Matthew Tallaferro, PhD

Control of cell division through centrosomal RNA localization

 $     30,000

2020

Diana M. Cittelly, PhD

Function of Ephrin B Signaling in Breast cancer brain metastasis

 $     30,000

2020

Rebecca Schweppe, PhD

The role of Nuclear FAK in Thyroid Cancer

 $     30,000

2020

Maureen Lynch, Phd & Philip Owens, PhD

The role of exercise in breast cancer bone metastasis

 $     60,000

2020

Christine Towers, PhD

Identifying novel regulators of mitochondrial turn over

 $     30,000

2020

Sujatha Venkataraman PhD & Adam Green, MD & Mark Kohler, MD, PhD

Engineering Logic-Gated DC99 CAR to selectively target H3K27M-DIPG tumor cells and to protect normal cells

 $     60,000

2020

Mayumi Fujita, MD, PhD & Charles A. Dinarello, MD

The role of alpha-1 antitrypsin in cancer immunotherapy

 $     60,000

2020

Raphael Nemenoff, PhD & Erin Schenk, MD, PhD

The Tumor Microenvironment as a Critical  Regulator of Targeted Therapy in ALK Positive Lung Cancer

 $     60,000

2020

Heather Brechbuhl, PhD

Defining reversible tumor traits in the obese microenvironment

 $              30,000

2019

Carol Sartorius, PhD

PR-RAR downregulation of protein synthesis and cell growth in breast cancer

 $              30,000

2019

Cem Altunbas, PhD

High-fidelity volumetric imaging for quantitative treatment monitoring and modifications in radiation therapy

 $              30,000

2019

Isabel Schlaepfer, PhD

Role of fat oxidation via CPT1A in immunological response to prostate cancer

 $              30,000

2019

Paul Norman, PhD

Natural Killer cells can protect from developing leukemia

 $              30,000

2019

Zachary Levi Watson, PhD

Targeting histone acetylation in PARP inhibitor-resistant ovarian cancer

 $              30,000

2019

John Tentler, PhD

Cancer Research Summer Fellowship Program

 $              30,000

2019

Adam Mueller, MD, PhD

Investigating crosstalk between ADAM10 and EphrinB2/EPHB4 in mediating radiation induced fibrosis, invasion and metastasis in pancreatic cancer

 $              30,000

2019

Jay Hesselberth, PhD

Single-cell methods to measure functional heterogeneity

 $              30,000

2019

Sujatha Venkataraman, PhD and Mark Kohler, MD, PhD

CD99 targeting CAR T cells as a novel therapy for H3K27M mutant DIPG

 $              60,000

2019

Shi-Long Lu, MD, PhD and Daniel Frank, PhD

Mechanism of oral microbiota in head and neck cancer pathogenesis and application for targeted therapy

 $              60,000

2019

Yiqun Shellman, PhD & Martin McCarter, MD

Targeting anti-apoptotic pathways to improve immunotherapies for melanoma

 $              60,000

2019

Mayumi Fujita, MD, PhD  & Donald Backos, PhD

Somatic mutations in inflammasome genes in melanoma

 $              60,000

2019

Neil Box, PhD

Regulation of p53 in tanning

 $              30,000

2019

Neelanjan Mukherjee, PhD & Daniel Sherbenou, MD, PhD

Exploiting mRNA translation inhibition for the treatment of relapsed/refractory multiple myeloma

 $              60,000

2019

Rajeev Vibhakar, MD, PhD, MPH

Role of CDK7 in medulloblastoma

 $              30,000

2019

Stephen Keysar, PhD

Targeting of stemness factors and fusion proteins in salivary gland cancers through inhibition of translation elongation

 $              30,000

2019

Matthew Sikora, PhD

Defining MDC1 as a central regulator of estrogen receptor and DNA repair in lobular carcinoma

 $              30,000

2019

Jennifer DeLuca, PhD

Targeting Kinetochore Dysfunction in Cancer Cells

 $     30,000

2018

David Thomas, PhD and Mark Borden, PhD

X-Ray Acoustic Computed Tomography Guided Adaptive Radiotherapy

 $     30,000

2018

Maria Jose Contreras, PhD

Mechanisms of TDM1/radiation-induced toxicity in brain metastases

 $     30,000

2018

Nathan Dahl, MD

Oncogenic Role of the Super Elongation Complex in H3K27M-mutant Diffuse Midline Glioma

 $     30,000

2018

Adwitiya Kar, PhD and Margaret Wierman, MD

Targeting Maternal Embryonic Leucine Zipper Kinase (MELK) in the first pre-clinical models of Adrenocortical Carcinoma

 $     30,000

2018

Courtney Jones, PhD

Targeting relapse leukemia stem cells through inhibition of NAD synthesis

 $     30,000

2018

Mair E.A. Churchill, PhD

Inhibition of Chromatin Assembly Factor 1 B to Reverse Leukemogenesis

 $     30,000

2018

Jessica Lake, MD, MPH

IPS-derived, CAR-expressing Natural Killer Cells Targeting EGFR on Pediatric Sarcomas

 $     30,000

2018

Jill Slansky PhD

Functional activation of low-affinity T cells in the tumor

 $     30,000

2018

Raul M. Torres, PhD

Suppression of human CD8 T cell antigen receptor signaling and cytotoxic activity by lysophosphatidic acid

 $     30,000

2018

Christopher Lieu, MD and Todd Pitts, MD

Investigating the role of MEK and non-canonical Wnt inhibition in altering the immune microenvironment in metastatic colorectal cancer

 $     60,000

2018

Linda Van Dyk, PhD

Role of CDK4 and CDK6 in gammaherpesvirus oncogenesis

 $     30,000

2018

Benjamin Bitler, PhD

Investigating the mechanisms of EHMT1/2-dependent PARP inhibitor resistance

 $     30,000

2018

Jennifer Hintzsche, PhD

Patient-centric Multi-Omics Approach to Identifying Actionable Therapeutics in Cancer

 $     30,000

2018

Martin McCarter, MD

Improving immune checkpoint inhibitor efficacy by targeting myeloid-derived suppressor cell function

 $     30,000

2018

David Ryan Ormond MD

Diffusion tensor image tractography in surgical resection of glioblastoma resection and surgical safety

 $     30,000

2018

Zhangguo Chen, PhD

Elucidating mechanisms by which a newly developed HDAC inhibitor sensitizes B cell lymphomas to PD-1 therapy

 $     30,000

2018

John Tentler, PhD

Cancer Research Summer Fellowship Program

 $     30,000

2018

Rebecca Schweppe, PhD

Cooperative Src and MAP Kinase Signaling in Thyroid Cancer

 $     30,000

2018

Scott Cramer, PhD and James Costello, PhD

Targeting the Achilles heel of prostate cancer with loss of CHD1 and MAP3K7

 $     60,000

2018

Katja Kiseljak-Vassiliades, DO and Kimberly Jordan, PhD

Potentiating anti-PD1 Immunotherapy with Mitotane in Adrenocortical Carcinoma

 $     60,000

2018

Nicholas Forman, MD

Characterization of heterogeneous tumor subpopulations in childhood ependymoma

 $     30,000

2018

Daniel V. LaBarbera, PhD and Wells A. Messersmith, MD

Patient Derived Tumor Organoids for Personalized and Targeted Colorectal Cancer Therapeutics

60,000

2017

Jung-Jae Lee, PhD

Storable, Thermally Activated, Self-Illuminating Nanoparticles Optical Imaging of Cancer

29,835

2017

Darinee Tippimanchai, PhD

Targeting IL17 in Kras mutant lung cancer

30,000

2017

Jenna Sopfe, MD

Evaluation of Malgylcemia via Continuous Glucose monitoring in the Pediatric Hematopoietic Stem Cell Transplant Population

29,961

2017

John Tentler, PhD

Cancer Research Summer Fellowship Program

30,000

2017

Rebecca Schweppe, PhD

Targeting FAK and Src in Thyroid Cancer

30,000

2017

Matthew J. Sikora, PhD

Exploiting apoptotic vulnerability in anti-estrogen response and resistance in invasive lobular carcinoma

30,000

2017

Jing H. Wang, MD, PhD

Elucidate novel mechanisms of chemotherapy agent-treated lymphomas to activate immune responses

30,000

2017

Kasey Couts, PhD

Improving targeted therapy in melanomas with BRAF fusions

30,000

2017

Britta Jacobsen, PhD

Examining the role of c-Kit in metastasis of Invasive Lobular Breast Cancer

30,000

2017

Eric Clambey, PhD

High-dimensional analysis of effector T cell mechanisms in lung cancer

30,000

2017

Heide L. Ford, PhD

Role of Six2 in mediating late stage metastasis

30,000

2017

Paul Jedlicka, MD, PhD

The epigenetic modifiers PHF2 and PhF8 in Ewing Sarcoma

30,000

2017

Changwei Liu, PhD

Validating USP35 as an anticancer drug target

30,000

2017

Hyunmin Kim, PhD

Systematic Alternative Splicing Analysis for Trancriptomic Misregulation in Cancer

30,000

2017

David Bentley, PhD

Deregulation of mRNA 3′ end formation in breast cancer

30,000

2017

Dan Theodorescu, MD, PhD

Whole genome knockout screening to identify novel TERT regulators with prognostic relevance in bladder cancer patients

30,000

2017

Todd Hankinson, MD, MBA

Comparison of Adult Adamantinomatous Craniopharyngioma Gene Expression with Known Pediatric Gene Expression

27,976

2017

Sana Karam, MD, PhD

Enhancing the Effects of Immune Checkpoint Blockade with Radiation Therapy in Head and Neck Cancer

30,000

2017

Amanda C. Winters, MD, PhD

Validating CD123 as a Leukemia Stem Cell Marker and Therapeutic Target in Pediatric AML

30,000

2017

James Costello, PhD

Measuring chromosome-conformation abnormalities within a single cancer cell

30,000

2017

Traci R. Lyons, PhD and      Beth Taburini, PhD

Evaluating the role of pro-lymphangiogenic factor Sem7a in dampening anti-tumor immunity

60,000

2017

James DeGregori, PhD

Understanding how smoking alters selection for common oncogenic mutations in the genesis of lung cancer

30,000

2017

Isabel Schlaepfer, PhD

Role of androgens on lipid catabolism in prostate cancer

30,000

2016

Scott Alper, PhD and Daniel Pollyea, MD, MS

Splicing gene mutations and infection in MDS patients

30,000

2016

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