A growing body of evidence suggests that ovarian cancer begins in the fallopian tubes and not the ovaries, giving researchers hope for developing better strategies to prevent and detect the deadly cancer, according to a story in the Wall Street Journal by Sumathi Reddy.
Among women with cancer, ovarian cancer is the fifth-leading cause of death, killing 14,000 American women a year. With no real way to screen for it, it usually isn’t diagnosed until it has spread and is in the later stages.
Two studies published last fall in the journal Nature Communications focused on high-grade serous ovarian cancer, the most common and serious type. Douglas Levine, director of gynecologic oncology at the Perlmutter Cancer Center at NYU Langone Health in New York City, with co-researchers examined precursor lesions, which are an abundance of abnormal cells, and the genetic profiles of tumors from 96 women with ovarian cancer.