Research Grants Awarded

Cancer League of Colorado 2014 Research Grants
Researcher Organization Grant Awarded
Carol Sartorius, PhD University of Colorado Denver Quiescent estrogen receptor positive cells as a source of breast cancer recurrence                   $30,000
Tobia Neff, MD University of Colorado Denver Novel Therapeutic Targets in Ezh2-Inactivated Acoute Leukemia                     $30,000
Christopher Porter, MD/ Jill Slansky, PhD University of Colorado Denver Leukemia-cell Calcineurin as a central mediator of immune evasion                     $60,000
John Tentler, PhD University of Colorado Denver Cancer Research Summer Fellowship Program                     $30,000
Lingdi Zhang, PhD University of Colorado Denver The effect of inhibiting splicing factor Snu114 in cancer                     $30,000
Rui Zhao, PhD / Heide Ford, PhD University of Colorado Denver Developing stapled peptides for breast cancer theraphy                     $60,000
James Finigan, MD / Aik Choon Tan, PhD National Jewish Hospital Kinome Essential Screen for Discovery of Novel Targets in Small Cell Lung Cancer                     $60,000
Maranke Koster, PhD University of Colorado Denver Consequences of TP63 loss on human skin squamous cell carcinogenesis                     $30,000
James Hagman, PhD National Jewish Hospital Functional analysis of EBF1:PDGFRB, a novel oncoprotein                     $30,000
Jing Hong Wang, PhD University of Colorado Denver A Novel Approach to Reveal the Impact of Genetic Mutations on Cancer Genome Stability                     $30,000
Martin McCarter, MD University of Colorado Denver Combined ATRA and Ipillmuma treatment to reduce immunosuppression in melanoma patients                     $30,000
Rebecca Schweppe, PhD / Bryan Haugen, MD University of Colorado Denver Targeting Src kinase with dasatinib in thryoid cancer                     $60,000
Lee Niswander, PhD University of Colorado Denver Grhl2 Developmental Network to Identify Novel Suppressors of EMT in Breast Cancer                     $60,000
Daniel Merrick, MD Denver Research Inst. Characterizing the activation status of inflammatory infiltrates in persistent and regressive premalignanat bronchial dysplasia                     $30,000
Cheng-jun Hu, PhD University of Colorado Denver Role of PBRM1 mutation in clear cell renal cell carcinoma                     $30,000
Michael Morgan, PhD University of Colorado Denver Autophagy and RIP#-dependent necrosis in cancer chemotherapy                     $30,000
Rytis Prekeris, PhD University of Colorado Denver Elucidating the roles of midbodies during squamous cell carcinoma progression                     $60,000
Sunny Guin, PhD University of Colorado Denver HAS2 is a critical effector for AGL mediated regulation of tumor growth                     $30,000
Dohun Pyeon, PhD University of Colorado Denver The Roles of APOBEC3 in Human Papillomavirus Infection and Oncogenesis                     $30,000
Paul Jedlicka, PhD University of Colorado Denver Evaluation of pharmacologic inhibition of histone demethylases in Ewing Sarcoma                     $30,000
Tullia Bruno, PhD University of Colorado Denver The function of tumor infiltrating B cells in non small cell lung cancer patients                     $30,000
Total $810,000

 

2013 CANCER LEAGUE OF COLORADO RESEARCH GRANTS

Download the 2013 the Rsearch Grants Awarded by the Cancer League of Colorado as a .pdf

Applicant 2013 Research Grant   Grant Amount
John Tentler PhD Cancer Research Fellowship Program UCD  $30,000
Eric Clambey PhD Role of hypoxic signaling in influencing T cell mediated cancer immunotherapy UCD $30,000
Elaine Lam and Aik Choon Tan Genomic sequencing-based predictive biomarker development for targeted anti- cancer therapies UCD $60,000
Ke Jun Han PhD with Changwei Liu Regulating EGFR protein levels by a deubiquitinaying enzyme in cancer cells UCD $30,000
Marybeth Sechler H3K9 histone demethylases in Ewing Sarcoma UCD $30,000
Chu An Wang, Dept. of Pharm. Targeting Vascular Endothelial Growth Factor C in the cancer stem like population sensitizes breast Ccncer cells to oxidize stress and onhibits tumor progression UCD $30,000
Todd McKinley director Collaborative Project to increase accrual to cancer trials CCRP $30,000
Thomas Rodger, postdoctoral fellow Targeting the Kynurenine Pathway to inhibit breast cancer metastases UCD $30,000
Xuedong Liu PhD Profile specific HDAC inhibitors for triple negative breast cancer UC Boulder $30,000
Nicholas Foreman MD Development of Antibody as immunotherapy for pediatric brain tumors UCD $30,000
Sunny Guin, Fellow AGL, a glycogen debranching gene is a novel suppressor of bladder cancer growth UCD $28,500
Elizabeth Kessler MD, Fellow Effects of Androgen Deprivation Therapy on geriatric health and physical function in men over 70 years of age with prostate cancer UCD $30,000
Lindsey Hoffman DO Unique patterns of progression in recurrent pediatric Ependymoma UCD $30,000
York Miller MD and Mark Geraci MD Bronchial Somatic Chromosomal Alterations in lung cancer risk UCD $30,000
Quinghong Zang PhD Targeting Melanoma Photocinogeneses by blocking C+BP1 UCD $30,000
Philip Reigan PhD and Heide Ford PhD Novel allosteric inhibitors of Eya 2 phosphate for treatment of metastatic breast cancer UCD $60,000
Steven Anderson and Mary Reyland Protein Kinase C Delta and breast cancer therapeutics UCD $30,000
Shi-Long Lu MD In Vivo modeling of salivary gland tumor formation progression UCD $30,000
Robert Keith MD with Gregory Hickey, Fellow Pre-Clinical Investigation of Treprostinil as a Cemopreventive Agent for non-small cell lung cancer VA $30,000
Daniel A. Pollyea MD A dose escalation study of Ibrutinib with Lenalidomide for relapsed and refractory chronic lymphocytic leukemia/small lymphocytic lymphoma UCD $30,000
Joy Hesselberth PhD Defining the role of SF 381 mutations in Leukemia UCD $30,000
Cheng-Jun Hu PhD Role of HIF in regulating RNI splicing of HIF target genes UCD $30,000
Christopher Lieu MD Discovery of novel targets for young patients with colorectal cancer UCD $30,000
Andrew Thorburn MD with Paola Maybeth, Fellow Targeting autophagy for the treatment of triple negative breast cancer UCD $30,000
Michael Graner PhD Metabolomics of primary and recurrent high grade gilomas: a role for the UPR UCD $30,000
TOTAL  $808,500

2012 CANCER LEAGUE OF COLORADO RESEARCH GRANTS

Download the 2012 CANCER LEAGUE OF COLORADO RESEARCH GRANTS as a .pdf

Pepper Schedin, PhD University of Colorado Denver
Investigating the role of lymphangiogenesis and lymphovascular invasion in metastasis of postpartum breast cancer
$30,000.00

Jingshi Shen, PhD
Dissection of the perforin pathway in cancer immunotherapy
$30,000.00
University of Colorado Boulder

Shi-Long Lu, PhD
Tumor cell Dissemination and Metastasis Initiation in Head and Neck Cancer
$30,000.00
University of Colorado Denver

Amanda Guth, DVM, PhD
Monocyte Blockade with CCR2 Antagonists for Inhibition of tumor metastases
$30,000.00
Colorado State University

Jill Slansky, PhD Tullio Bruno, PhD
Characterizing the Function and Location of B Cells in Lung Cancer
$30,000.00
University of Colorado Denver

Jordan Jacobelli, PhD
Regulation of lymphoma dissemination by the actin-myosin cytoskeleton
$30,000.00
National Jewish Health

Eduardo Pajon, MD
Colorado Cancer Research Program
$30,000.00
Presbyterian/St. Luke’s

Rui Zhao, PhD Quinghong Zhang, PhD
Inhibiting the transcriptional co-repressor CtBP for cancer therapy using cell penetrating peptide
$60,000.00
University of Colorado Denver

Catherine Musselman, PhD
The Role of PHF1 in the repressive activity of PRC2
$30,000.00
University of Colorado Denver

Ann Thor, MD/ Reema Wahdan-Alaswad, PhD
Metformin Inhibits Metastasis in Triple Negative Breast Cancer
$30,000.00
University of Colorado Denver

Marileila Varella Garcia, PhD
2012 Cancer Research Summer Fellowship Program
$30,000.00
University of Colorado Denver

Peter Kabos, MD
Role of alternative polyadenylation in estrogen receptor positive breast cancer
$30,000.00
University of Colorado Denver

Michael J. Morgan, PhD
Autophagy Dependence and Chloroquine Sensitivity in Metastatic Cancer
$30,000.00
University of Colorado Denver

Stephen Malkoski, MD Scott Cramer, PhD
Defining the role of TAK1 in non-small cell lung cancer
$60,000.00
University of Colorado Denver

Antonio Jimeno, MD, PhD Gregory Gan, MD, PhD
Resistance of Human Head and Neck Squamous Cell Carcinoma to Concurrent EGFR and Radiotherapy Mediated Through the Hedgehog Pathway
$30,000.00
University of Colorado Denver

Bolin Liu, MD
Epignetic induction of erbB2/erbB3-targeting miRNAs in breast cancer
$30,000.00
University of Colorado Denver

Robert Doebele, MD, PhD Kurtis D. Davies, PhD
Acquired Resistance to ROS1 inhibition in Non-Small Cell Lung Cancer: Identification of Cellular Mechanisms and Exploration of Alternative Treatment Strategies
$30,000.00
University of Colorado Denver

David Astling, PhD
Development of an Improved Classifier for Predicting Multiple Drug Classes and Molecular Targets for Tumor Subtypes
$30,000.00
University of Colorado Denver

Uday Kompella, PhD
Novel Lung Cancer Therapeutics
$30,000.00
University of Colorado Denver

Michelle Guney, PhD
The Role of Eya in breast cancer metastic progression
$30,000.00
University of Colorado Denver

Colin Moore, MD
Evaluating the Role of miR 193b in Ewing Sarcoma growth Suppression
$30,000.00
University of Colorado Denver

Caroline Kulesza, PhD
Virus Manipulation of a Cellular Chromatin Modifying Complex
$30,000.00
University of Colorado Denver
$720,000.00

2011 CANCER LEAGUE OF COLORADO RESEARCH GRANTS

2011 Awards

Steve Anderson, Ph.D.
University of Colorado Denver
Does cell surface transporter expression determine the response of breast cancer
$30,000
Sunshine Axlund, Ph.D.
University of Colorado Denver
Tumor initiating and Drug Resistant Properties of a minor Population of Stem-Like Cells in Explant Models of Estrogen Receptor Positive Human Breast Tumors

$30,000

Andrew Bradford, Ph.D.
University of Colorado Denver
PKCδ as a biomarker and regulator of response to chemotherapy in endometrial cancer

$30,000
Dawn Cochrane, Ph.D.
University of Colorado Denver
Restoring miR-200c to aggressive ovarian cancers to attack anoikis resistance
$30,000
Dawn Duval, Ph.D.
Colorado State University
Osteosarcoma: Biomarkers of Metastasis and Resistance to Therapy
$30,000
Kim Jihye, Ph.D.
University of Colorado Denver
PathCMap Development of pathway signature system for identifying partners of synethetic lethal genes
$30,000
James Lambert, Ph.D.
University of Colorado Denver
Genome-wide RA interference screen for mediators of cell death induced by a novel vitamin D analog in triple negative breast cancer
$30,000
Lindsay Micel, M.D.
University of Colorado Denver
Identifying mechanisms of resistance to the novel NAE inhibitor, MLN4924, in melanoma

$30,000
Christopher Porter, M.D. and Jean Mulcahy, M.D.
University of Colorado Denver UCD
High Throughput Functional Genetic Screening to Define the Role of Autophagy in Pediatric Brain Tumors

$60,000
Pajon, Eduardo, Jr., M.D.
CO Cancer Research Program
Colorado Cancer Research Clinical Trials Program
$30,000
Renee Paulson, Ph.D.
University of Colorado Boulder
Elucidating the cellular response to hypoxia via functional genomics

$30,000
Rytis Prekeris, Ph.D., and Pepper Schedin, Ph.D.
University of Colorado Denver
The regulation of MMP Secretion During the Invasion of Breast Cancer Cells
$60,000
Dylan Taatjes, Ph.D.
University of Colorado Boulder
Identification of transcriptional cofactors that trigger alternations in breast cancer pathology and therapeutic response
$30,000
Raul Torres, Ph.D.
University of Colorado Denver
LPA Regulation of T Cell Tumor Immunity
$30,000
Marileila Varella Garcia, Ph.D.
University of Colorado Denver
Cancer Research Summer Fellowship Program

$30,000
Henry Thompson, Ph.D. and Barbara Wallner, Ph.D.
Colorado State University
Competency Development to Reduce Obesity and Promote Long Term Survival Following treatment for Breast Cancer

$59,780
Quinghong Zhang, Ph.D.
University of Colorado Denver
The Role of CtBP1 in SCC

$30,000